In March 1969, Paul McCartney married Linda Eastman at Marylebone Registry office.

The first heart transplant in the UK took place on the 3rd of May, 1968 at the National Heart Hospital in Marylebone.

Famous residents of Marylebone include Charles Dickens, John Lennon and Yoko Ono, Ringo Starr, Paul McCartney, H. G. Wells, Barbara Windsor and Madonna.

Jimi Hendrix lived at 43 Upper Berkeley Street, Marylebone.

Florence Nightingale was Superintendent of the Establishment for Gentlewomen at No. 1 Harley Street, Marylebone in 1853.